Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. 2023 Lybrate, Inc. All rights reserved. See also: nitroglycerin side effects in more detail. Take this medication by mouth as directed by your doctor, usually twice a day. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). It is important that you follow the instructions your doctor gives to you about when to take your doses. Saper RB. What side effects can this medication cause? MeSH Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Generic alternatives may be available. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. This content does not have an English version. 19 are major, 174 are moderate, and 2 are minor. We comply with the HONcode standard for trustworthy health information. What happens if I stop taking isosorbide mononitrate (Monoket)? When used regularly on a long-term basis, this helps prevent angina attacks from occurring. This site complies with the HONcode standard for trustworthy health information: verify here. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Do not stop taking it without consulting your doctor. Bookshelf To help you remember, take it at the same times each day. Canada residents can call a provincial poison control center. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). You may report side effects to the FDA at 1-800-FDA-1088. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. isosorbide mononitrate prices. (2) One in 3 patients never experienced headache from the given dosages. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. The two dosage regimens were equally efficient for the relief of angina pectoris without development of tolerance. Other medications may be prescribed by your doctor for these conditions. Natural remedies for depression: Are they effective? tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Does Isosorbide Mononitrate interact with other drugs you are taking? Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. In: Current Medical Diagnosis & Treatment 2022. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Isosorbide mononitrate (Monoket) is not known to affect the kidneys. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. If you become pregnant while taking isosorbide, call your doctor. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Natural Medicines. This should pass after a few days. Prescribed for Angina, Anal Fissure and Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. The most common side-effect is headache. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. https://naturalmedicines.therapeuticresearch.com. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Diabetes treatment: Can cinnamon lower blood sugar? Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. Please note that only the generic name of each medication is listed below. Accessed Sept. 7, 2022. Browse all drugs on eHealthMe. Ginkgo. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Ask your pharmacist for a list of the ingredients. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). What conditions does Isosorbide Mononitrate treat? ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. 67% of reviewers reported a positive effect, while 13% reported a negative effect. If you notice any other effects, check with your healthcare professional. Would you like email updates of new search results? Then, there was a two-week placebo washout, after which the alternative treatment was given. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). What special dietary instructions should I follow? Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Do not keep out-of-date or unwanted medicines. This medicine is available only with your doctor's . If you forget to take a dose, take it as soon as you remember. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. Isosorbide mononitrate helps to prevent angina chest pain from developing. All rights reserved. Browse Drugs and Medicines. If you have ever had an allergic reaction to a medicine. Does isosorbide mononitrate (Monoket) affect your kidneys? Prescription and OTC If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . This site complies with the HONcode standard for trustworthy health information: verify here. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Cleophas TJ, Niemeyer MG, van Der Wall EE. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Epub 2006 Mar 22. Use this medication regularly to get the most benefit from it. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. government site. Change positions slowly until your body is used to the medication. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Journal of the American College of Cardiology. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. National Library of Medicine This information is aggregated and used to produce personalized reports that patients can reference. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. It has a very short duration of action and may not be suitable for some people. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. May also be prescribed off label for Esophageal Spasm. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Consult your pharmacist or local waste disposal company. Mayo Clinic. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. Accessed Sept. 7, 2022. If this worries you, talk to your doctor or pharmacist about other options. If you suffer headaches when taking Isosorbide mononitrate, be patient. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Drug information provided by: IBM Micromedex. Natural Medicines. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. What should I know about storage and disposal of this medication? Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). Keep all medicines out of the reach and sight of children. Although not all of these side effects may occur, if they do occur they may need medical attention. Isosorbide mononitrate works in two ways. The .gov means its official. The table below contains some of the most common ones associated with isosorbide mononitrate. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . It will not treat an angina attack that has already begun. Overview of herbal medicines and dietary supplements. The effects of this exposure on a nursing infant are unknown. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. Consult your doctor before breast-feeding. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. These side effects may go away during treatment as your body adjusts to the medicine. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Does isosorbide mononitrate (Monoket) lower blood pressure? It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. https://naturalmedicines.therapeuticresearch.com. The dose is according to the body weight and severity of the condition. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. The extended-release capsule usually is taken once daily. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Your dose may need to be gradually decreased. It is components of vit. But only about 25% of people who take herbal supplements tell their health care providers. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. There may be variations in CSA schedules between individual states. Hawthorn. Using this medicine with any of the following medicines is not recommended. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. This survey is being conducted by the WebMD marketing sciences department. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Take them to your local pharmacy which will dispose of them for you. Herbal supplements can strongly affect the body. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. This product is available in the following dosage forms: There is a problem with Things to remember when you fill your prescription. This is not a complete list of possible side effects. Enter other medications to view a detailed report. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Selected from data included with permission and copyrighted by First Databank, Inc. official website and that any information you provide is encrypted Who should not take Isosorbide Mononitrate? Do not store in the bathroom. Yet many herbal supplements may interact with heart disease medicines. Accessed Sept. 7, 2022. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. Store at room temperature away from light and moisture. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. [2] It is taken by mouth. Results: https://naturalmedicines.therapeuticresearch.com. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. Copyright 2023 IBM Watson Health. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. It works and leaves the body quickly, so it needs to be taken twice a day. The https:// ensures that you are connecting to the You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Advertising revenue supports our not-for-profit mission. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients.
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